Stachyose: One of the Active Fibroblast-proliferating Components in the Root of Rehmanniae Radix (地黃 dì huáng)
Identifieur interne : 003E66 ( Main/Exploration ); précédent : 003E65; suivant : 003E67Stachyose: One of the Active Fibroblast-proliferating Components in the Root of Rehmanniae Radix (地黃 dì huáng)
Auteurs : Patrick Kwok-Kin Lai ; Ming-Ho To ; Kit-Man Lau ; Cheuk-Lun Liu ; Ling Cheng ; Kwok-Pui Fung [Hong Kong] ; Ping-Chung Leung ; Clara Bik-San LauSource :
- Journal of Traditional and Complementary Medicine [ 2225-4110 ] ; 2012.
Abstract
This study aimed to investigate and compare the fibroblast-proliferating activities of different Rehmanniae Radix (RR) samples and its chemical components using human normal fibroblast cells Hs27. Those active components were quantified in differently treated RR samples using UPLC so as to correlate activity with component content. Our results showed that dried RR aqueous extract exhibited the most potent fibroblast-proliferating activity. Stronger effect was observed when ethanol with heating was applied in the extraction process. Stachyose and verbascoside were demonstrated for their first time to exhibit significant stimulatory effects on fibroblast proliferation. However, the proliferating effect of dried RR extract did not correlate with the stachyose content, and verbascoside was not responsible for the fibroblast proliferative effect of RR since it was undetectable in all samples. In conclusion, stachyose only contributed in part to the activity of RR, suggesting that other active components might be present and yet to be found.
Url:
PubMed: 24716137
PubMed Central: 3942900
Affiliations:
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</title><author><name sortKey="Lai, Patrick Kwok Kin" sort="Lai, Patrick Kwok Kin" uniqKey="Lai P" first="Patrick Kwok-Kin" last="Lai">Patrick Kwok-Kin Lai</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="To, Ming Ho" sort="To, Ming Ho" uniqKey="To M" first="Ming-Ho" last="To">Ming-Ho To</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="Lau, Kit Man" sort="Lau, Kit Man" uniqKey="Lau K" first="Kit-Man" last="Lau">Kit-Man Lau</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="Liu, Cheuk Lun" sort="Liu, Cheuk Lun" uniqKey="Liu C" first="Cheuk-Lun" last="Liu">Cheuk-Lun Liu</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="Cheng, Ling" sort="Cheng, Ling" uniqKey="Cheng L" first="Ling" last="Cheng">Ling Cheng</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="Fung, Kwok Pui" sort="Fung, Kwok Pui" uniqKey="Fung K" first="Kwok-Pui" last="Fung">Kwok-Pui Fung</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation><affiliation wicri:level="4"><nlm:aff id="aff3">School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Leung, Ping Chung" sort="Leung, Ping Chung" uniqKey="Leung P" first="Ping-Chung" last="Leung">Ping-Chung Leung</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author><author><name sortKey="Lau, Clara Bik San" sort="Lau, Clara Bik San" uniqKey="Lau C" first="Clara Bik-San" last="Lau">Clara Bik-San Lau</name><affiliation><nlm:aff id="aff1">Institute of Chinese Medicine;</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">State Key Laboratory of Phytochemistry & Plant Resources in West China (CUHK);</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Traditional and Complementary Medicine</title><idno type="eISSN">2225-4110</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>This study aimed to investigate and compare the fibroblast-proliferating activities of different Rehmanniae Radix (RR) samples and its chemical components using human normal fibroblast cells Hs27. Those active components were quantified in differently treated RR samples using UPLC so as to correlate activity with component content. Our results showed that dried RR aqueous extract exhibited the most potent fibroblast-proliferating activity. Stronger effect was observed when ethanol with heating was applied in the extraction process. Stachyose and verbascoside were demonstrated for their first time to exhibit significant stimulatory effects on fibroblast proliferation. However, the proliferating effect of dried RR extract did not correlate with the stachyose content, and verbascoside was not responsible for the fibroblast proliferative effect of RR since it was undetectable in all samples. In conclusion, stachyose only contributed in part to the activity of RR, suggesting that other active components might be present and yet to be found.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Adolphe, M" uniqKey="Adolphe M">M. Adolphe</name></author><author><name sortKey="Pointet, Y" uniqKey="Pointet Y">Y. Pointet</name></author><author><name sortKey="Ronot, X" uniqKey="Ronot X">X. Ronot</name></author><author><name sortKey="Wepierre, J" uniqKey="Wepierre J">J. Wepierre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Armstrong, D G" uniqKey="Armstrong D">D.G. Armstrong</name></author><author><name sortKey="Lavery, L A" uniqKey="Lavery L">L.A. Lavery</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bilia, A R" uniqKey="Bilia A">A.R. Bilia</name></author><author><name sortKey="Giomi, M" uniqKey="Giomi M">M. Giomi</name></author><author><name sortKey="Innocenti, M" uniqKey="Innocenti M">M. Innocenti</name></author><author><name sortKey="Gallori, S" uniqKey="Gallori S">S. Gallori</name></author><author><name sortKey="Vincieri, F F" uniqKey="Vincieri F">F.F. Vincieri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bucalo, B" uniqKey="Bucalo B">B. Bucalo</name></author><author><name sortKey="Eaglstein, W H" uniqKey="Eaglstein W">W.H. Eaglstein</name></author><author><name sortKey="Falanga, V" uniqKey="Falanga V">V. Falanga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, W" uniqKey="Guo W">W. Guo</name></author><author><name sortKey="Wen, X S" uniqKey="Wen X">X.S. Wen</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y. Wang</name></author><author><name sortKey="Zhao, Y" uniqKey="Zhao Y">Y. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hong, Y" uniqKey="Hong Y">Y. Hong</name></author><author><name sortKey="Wen, X S" uniqKey="Wen X">X.S. Wen</name></author><author><name sortKey="Gao, L" uniqKey="Gao L">L. Gao</name></author><author><name sortKey="Huang, Q W" uniqKey="Huang Q">Q.W. Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiangsu, Xinyiyuan" uniqKey="Jiangsu X">Xinyiyuan Jiangsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kalish, J" uniqKey="Kalish J">J. Kalish</name></author><author><name sortKey="Hamdan, A" uniqKey="Hamdan A">A. Hamdan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kubo, M" uniqKey="Kubo M">M. Kubo</name></author><author><name sortKey="Asano, T" uniqKey="Asano T">T. Asano</name></author><author><name sortKey="Matsuda, H" uniqKey="Matsuda H">H. Matsuda</name></author><author><name sortKey="Yutani, S" uniqKey="Yutani S">S. Yutani</name></author><author><name sortKey="Honda, S" uniqKey="Honda S">S. Honda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, T W" uniqKey="Lau T">T.W. Lau</name></author><author><name sortKey="Chan, Y W" uniqKey="Chan Y">Y.W. Chan</name></author><author><name sortKey="Lau, C P" uniqKey="Lau C">C.P. Lau</name></author><author><name sortKey="Chan, C M" uniqKey="Chan C">C.M. Chan</name></author><author><name sortKey="Lau, Cbs" uniqKey="Lau C">CBS Lau</name></author><author><name sortKey="Fung, K P" uniqKey="Fung K">K.P. Fung</name></author><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C. Leung</name></author><author><name sortKey="Ho, Y Y" uniqKey="Ho Y">Y.Y. Ho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, T W" uniqKey="Lau T">T.W. Lau</name></author><author><name sortKey="Chan, Y W" uniqKey="Chan Y">Y.W. Chan</name></author><author><name sortKey="Lau, C P" uniqKey="Lau C">C.P. Lau</name></author><author><name sortKey="Lau, K M" uniqKey="Lau K">K.M. Lau</name></author><author><name sortKey="Lau, Cbs" uniqKey="Lau C">CBS Lau</name></author><author><name sortKey="Fung, K P" uniqKey="Fung K">K.P. Fung</name></author><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C. Leung</name></author><author><name sortKey="Ho, Y Y" uniqKey="Ho Y">Y.Y. Ho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, T W" uniqKey="Lau T">T.W. Lau</name></author><author><name sortKey="Sahota, D S" uniqKey="Sahota D">D.S. Sahota</name></author><author><name sortKey="Lau, C H" uniqKey="Lau C">C.H. Lau</name></author><author><name sortKey="Chan, C M" uniqKey="Chan C">C.M. Chan</name></author><author><name sortKey="Lam, F C" uniqKey="Lam F">F.C. Lam</name></author><author><name sortKey="Ho, Y Y" uniqKey="Ho Y">Y.Y. Ho</name></author><author><name sortKey="Fung, K P" uniqKey="Fung K">K.P. Fung</name></author><author><name sortKey="Lau, Cbs" uniqKey="Lau C">CBS Lau</name></author><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C. Leung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C. Leung</name></author><author><name sortKey="Wong, M W" uniqKey="Wong M">M.W. Wong</name></author><author><name sortKey="Wong, W C" uniqKey="Wong W">W.C. Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levin, E" uniqKey="Levin E">E. Levin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, A S" uniqKey="Lin A">A.S. Lin</name></author><author><name sortKey="Qian, K D" uniqKey="Qian K">K.D. Qian</name></author><author><name sortKey="Usami, Y" uniqKey="Usami Y">Y. Usami</name></author><author><name sortKey="Lin, L" uniqKey="Lin L">L. Lin</name></author><author><name sortKey="Itokawa, H" uniqKey="Itokawa H">H. Itokawa</name></author><author><name sortKey="Susan, C H" uniqKey="Susan C">C.H. Susan</name></author><author><name sortKey="Morris Natschke, L" uniqKey="Morris Natschke L">L. Morris-Natschke</name></author><author><name sortKey="Lee, K H" uniqKey="Lee K">K.H. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, G W" uniqKey="Liu G">G.W. Liu</name></author><author><name sortKey="Lauda, D P" uniqKey="Lauda D">D.P. Lauda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Macdonald, J M" uniqKey="Macdonald J">J.M. Macdonald</name></author><author><name sortKey="Geyer, M J" uniqKey="Geyer M">M.J. Geyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mansbridge, J N" uniqKey="Mansbridge J">J.N. Mansbridge</name></author><author><name sortKey="Liu, K" uniqKey="Liu K">K. Liu</name></author><author><name sortKey="Pinney, R E" uniqKey="Pinney R">R.E. Pinney</name></author><author><name sortKey="Patch, R" uniqKey="Patch R">R. Patch</name></author><author><name sortKey="Ratcliffe, A" uniqKey="Ratcliffe A">A. Ratcliffe</name></author><author><name sortKey="Naughton, G K" uniqKey="Naughton G">G.K. Naughton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nishimura, H" uniqKey="Nishimura H">H. Nishimura</name></author><author><name sortKey="Sugama, K" uniqKey="Sugama K">K. Sugama</name></author><author><name sortKey="Morota, T" uniqKey="Morota T">T. Morota</name></author><author><name sortKey="Chin, M" uniqKey="Chin M">M. Chin</name></author><author><name sortKey="Mitsuhashi, H" uniqKey="Mitsuhashi H">H. Mitsuhashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, S G" uniqKey="Park S">S.G. Park</name></author><author><name sortKey="Shin, H" uniqKey="Shin H">H. Shin</name></author><author><name sortKey="Shin, Y K" uniqKey="Shin Y">Y.K. Shin</name></author><author><name sortKey="Lee, Y" uniqKey="Lee Y">Y. Lee</name></author><author><name sortKey="Choi, E C" uniqKey="Choi E">E.C. Choi</name></author><author><name sortKey="Park, B J" uniqKey="Park B">B.J. Park</name></author><author><name sortKey="Kim, S" uniqKey="Kim S">S. Kim</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tang, L" uniqKey="Tang L">L. Tang</name></author><author><name sortKey="Liu, L" uniqKey="Liu L">L. Liu</name></author><author><name sortKey="Xu, D S" uniqKey="Xu D">D.S. Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, G Q" uniqKey="Wang G">G.Q. Wang</name></author><author><name sortKey="Dong, C H" uniqKey="Dong C">C.H. Dong</name></author><author><name sortKey="Shang, Y K" uniqKey="Shang Y">Y.K. Shang</name></author><author><name sortKey="Sun, Y A" uniqKey="Sun Y">Y.A. Sun</name></author><author><name sortKey="Fu, D X" uniqKey="Fu D">D.X. Fu</name></author><author><name sortKey="Zhao, J B" uniqKey="Zhao J">J.B. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, M W" uniqKey="Wong M">M.W. Wong</name></author><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C. Leung</name></author><author><name sortKey="Wong, W C" uniqKey="Wong W">W.C. Wong</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Yoshikawa, M" uniqKey="Yoshikawa M">M. Yoshikawa</name></author><author><name sortKey="Fukuda, Y" uniqKey="Fukuda Y">Y. Fukuda</name></author><author><name sortKey="Taniyama, T" uniqKey="Taniyama T">T. Taniyama</name></author><author><name sortKey="Cha, B C" uniqKey="Cha B">B.C. Cha</name></author><author><name sortKey="Kitagawa, I" uniqKey="Kitagawa I">I. Kitagawa</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Hong Kong</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><noCountry><name sortKey="Cheng, Ling" sort="Cheng, Ling" uniqKey="Cheng L" first="Ling" last="Cheng">Ling Cheng</name><name sortKey="Lai, Patrick Kwok Kin" sort="Lai, Patrick Kwok Kin" uniqKey="Lai P" first="Patrick Kwok-Kin" last="Lai">Patrick Kwok-Kin Lai</name><name sortKey="Lau, Clara Bik San" sort="Lau, Clara Bik San" uniqKey="Lau C" first="Clara Bik-San" last="Lau">Clara Bik-San Lau</name><name sortKey="Lau, Kit Man" sort="Lau, Kit Man" uniqKey="Lau K" first="Kit-Man" last="Lau">Kit-Man Lau</name><name sortKey="Leung, Ping Chung" sort="Leung, Ping Chung" uniqKey="Leung P" first="Ping-Chung" last="Leung">Ping-Chung Leung</name><name sortKey="Liu, Cheuk Lun" sort="Liu, Cheuk Lun" uniqKey="Liu C" first="Cheuk-Lun" last="Liu">Cheuk-Lun Liu</name><name sortKey="To, Ming Ho" sort="To, Ming Ho" uniqKey="To M" first="Ming-Ho" last="To">Ming-Ho To</name></noCountry><country name="Hong Kong"><noRegion><name sortKey="Fung, Kwok Pui" sort="Fung, Kwok Pui" uniqKey="Fung K" first="Kwok-Pui" last="Fung">Kwok-Pui Fung</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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